823 research outputs found
The Research of Automation of the Process of Indexing Tax Returns
The article is devoted to the study of the automated search for information on tax declarations of different countries in public sources of various structures and the collection of information received in a single information storage. The first part of the paper describes methods of automated data collection and tasks that can be solved by these methods. The second part of the work describes the development of an algorithm for finding data on tax declarations from various sources and creating a prototype system that implements the data of the algorithm and provides access to the collected data.Β Keywords: search systems, indexation of tax declarations, information retrieval system
Import Substitution Production of Semiconductor Silicon in Russia as a Tool to Reduce the risk of Money Laundering
The work is devoted to studying the need of creation a domestic production of polycrystalline, monocrystalline silicon and silicon wafers for the purposes of electronics and solar energy in the Russian Federation, as a part of the solution of a number of strategic objectives. In addition, the work discusses the question of import substitution as a means of combating money-laundering.Β Keywords: semiconductor silicon, polycrystalline silicon, monocrystalline silicon, import substitution, money launderin
Development of an Automated Approach for Updating of the Annual Runoff Module Map
Several Russian Hydropower Design and Research Institutes have recently fulfilled studies of hydropower potential estimation for NorthWest, Caucasian and Angara Riverβs regions in Russia. An approach to automate the calculation of river flow characteristics, based on the usage of annual flow rate map, was proposed and tested by the authors for the aims of the studies.Annual river flow characteristics together with the terrain data are the most important data sources for evaluation of the hydropower potential.A set of requirements was made for the approach and for automation of annual flow rate maps creation in order to provide ability for updates in every 5-10 years.A problem of lack of hydrological data for small and medium sized rivers was faced. To determine the hydrological characteristics the Russian code specification "Determination of Design Hydrological Performance" was used for the conditions of the lack of hydrological data, methods of spatial interpolation were also used.To solve the problems it is necessary to define the parameters of the annual flow distribution: average annual flow, variation coefficient, coefficient of skewness.Mapping is based on the assumption of a smooth change of annual flow rate for any territory in accordance with the distribution of climatic and physiographic factors (topography, soil, groundwater depth, etc.).Milestones of flow rate mapping included: preparation of hydrological initial data; creating of the updated flow rate maps; determination of the corrections to the influence of local azonal factors; estimation of the accuracy of flow characteristics calculations.In order to update the annual flow rate maps a special GIS application βHydrologistβ was created. The GIS application includes computer-assisted tool for processing the hydrological data, import/export tools, tools for analysis of area zoning data, tools for analysis of annual flow rate values in centroids of drainage-basins, location of water stage gauges, also the old and updated flow rate maps.The article deals with the approach description, main problems that were faced and presenting the results.The technology has been applied for North-West, Volga and Siberian Federal Districts in Russia. Comparison of the created annual flow rate map with the previously used map shows that the updated map is better of acquiring hydrological data for small and medium sized rivers
Mid-range adiabatic wireless energy transfer via a mediator coil
A technique for efficient mid-range wireless energy transfer between two
coils via a mediator coil is proposed. By varying the coil frequencies three
resonances are created: emitter-mediator (EM), mediator-receiver (MR) and
emitter-receiver (ER). If the frequency sweeps are adiabatic and such that the
ER resonance precedes the MR resonance, the energy flows sequentially along the
chain emitter-mediator-receiver. If the MR resonance precedes the ER resonance,
then the energy flows directly from the emitter to the receiver via the ER
resonance; then the losses from the mediator are suppressed. This technique is
robust to noise, resonant constraints and external interferences
Identification of dynamic errors-in-variables bilinear systems of fractional order
An approach for the identification of dynamic single-input single-output bilinear
discrete-time fractional order system models within the errors-in-variables framework for the
case of white input and output noise sequences is presented. A criterion is obtained that allows
obtaining highly consistent estimates of the parameters of the system.The authors gratefully acknowledge the contributions of prof. O.A. Katsyuba in improving the article
Identification of dynamic errors-in-variables bilinear systems of fractional order
An approach for the identification of dynamic single-input single-output bilinear
discrete-time fractional order system models within the errors-in-variables framework for the
case of white input and output noise sequences is presented. A criterion is obtained that allows
obtaining highly consistent estimates of the parameters of the system.The authors gratefully acknowledge the contributions of prof. O.A. Katsyuba in improving the article
Primary Sequences of Protein-Like Copolymers: Levy Flight Type Long Range Correlations
We consider the statistical properties of primary sequences of two-letter HP
copolymers (H for hydrophobic and P for polar) designed to have water soluble
globular conformations with H monomers shielded from water inside the shell of
P monomers. We show, both by computer simulations and by exact analytical
calculation, that for large globules and flexible polymers such sequences
exhibit long-range correlations which can be described by Levy-flight
statistics.Comment: 4 pages, including 2 figures; several references added, some
formulations improve
Orbit equivalence rigidity for ergodic actions of the mapping class group
We establish orbit equivalence rigidity for any ergodic, essentially free and
measure-preserving action on a standard Borel space with a finite positive
measure of the mapping class group for a compact orientable surface with higher
complexity. We prove similar rigidity results for a finite direct product of
mapping class groups as well.Comment: 11 pages, title changed, a part of contents remove
Exact Lagrangian submanifolds in simply-connected cotangent bundles
We consider exact Lagrangian submanifolds in cotangent bundles. Under certain
additional restrictions (triviality of the fundamental group of the cotangent
bundle, and of the Maslov class and second Stiefel-Whitney class of the
Lagrangian submanifold) we prove such submanifolds are Floer-cohomologically
indistinguishable from the zero-section. This implies strong restrictions on
their topology. An essentially equivalent result was recently proved
independently by Nadler, using a different approach.Comment: 28 pages, 3 figures. Version 2 -- derivation and discussion of the
spectral sequence considerably expanded. Other minor change
ΠΡΡΠΎΠΊΠΎΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡΠ΅Π»ΡΠ½ΡΠΉ ΡΠΊΡΠΈΠ½ΠΈΠ½Π³ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΠΎΠΏΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ SPR-Π±ΠΈΠΎΡΠ΅Π½ΡΠΎΡΠ° Π½ΠΈΠ·ΠΊΠΎΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΡΡ ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ Π½Π° Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ Ρ CYP51 Candida krusei
The opportunistic fungus Candida krusei is the causative agent of nosocomial infections characterized by high mortality and development of resistance to drugs of the azole class. Therefore, develjoment of non-azole antifungal agents against resistant fungal strains is extremly important. Lanosterol 14-alpha demethylase (CYP51) is a well-known antifungal target. The optical SPR biosensor is a universal tool for screening studies in search of new drug prototypes. This paper presents the methodological aspects of high-hroughput SPR based screening of a library of low molecular weight compounds of natural origin for their interaction with C. krusei CYP51. It has been shown that when performing high-throughput screening, a researcher should pay special attention to the degree of a sensorgram curvature in the association phase. The described approaches to the analysis of high throughput screening data can be useful for researchers working with SPR biosensors from various manufacturers.Π£ΡΠ»ΠΎΠ²Π½ΠΎ-ΠΏΠ°ΡΠΎΠ³Π΅Π½Π½ΡΠΉ Π³ΡΠΈΠ± Candida krusei (C. krusei) ΡΠ²Π»ΡΠ΅ΡΡΡ Π²ΠΎΠ·Π±ΡΠ΄ΠΈΡΠ΅Π»Π΅ΠΌ Π½ΠΎΠ·ΠΎΠΊΠΎΠΌΠΈΠ°Π»ΡΠ½ΡΡ
ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΉ, Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΡΡΡΠΈΡ
ΡΡ Π²ΡΡΠΎΠΊΠΎΠΉ Π»Π΅ΡΠ°Π»ΡΠ½ΠΎΡΡΡΡ. Π ΠΏΠΎΡΠ»Π΅Π΄Π½Π΅Π΅ Π²ΡΠ΅ΠΌΡ Π½Π°Π±Π»ΡΠ΄Π°Π΅ΡΡΡ ΡΠ΅Π½Π΄Π΅Π½ΡΠΈΡ ΠΊ ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΡ Π΄ΠΎΠ»ΠΈ ΡΡΠ°ΠΌΠΌΠΎΠ² Π΄ΡΠΎΠΆΠΆΠ΅Π²ΡΡ
Π³ΡΠΈΠ±ΠΎΠ², ΡΠ΅Π·ΠΈΡΡΠ΅Π½ΡΠ½ΡΡ
ΠΊ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠ°ΠΌ ΠΊΠ»Π°ΡΡΠ° Π°Π·ΠΎΠ»ΠΎΠ². ΠΠΎΡΡΠΎΠΌΡ ΠΏΠΎΠΈΡΠΊ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΡΡ
ΠΏΡΠΎΡΠΈΠ²ΠΎΠ³ΡΠΈΠ±ΠΊΠΎΠ²ΡΡ
ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ Π½Π΅Π°Π·ΠΎΠ»ΡΠ½ΠΎΠΉ ΠΏΡΠΈΡΠΎΠ΄Ρ ΡΠ²Π»ΡΠ΅ΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΠΌ Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½ΠΈΠ΅ΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ ΠΏΡΠΈ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠ΅ Π½ΠΎΠ²ΡΡ
ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΡΠ΅ΡΠ°ΠΏΠ΅Π²ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΡΠ΅Π΄ΡΡΠ² Π² ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠΈ ΡΠ΅Π·ΠΈΡΡΠ΅Π½ΡΠ½ΡΡ
ΡΡΠ°ΠΌΠΌΠΎΠ² Π³ΡΠΈΠ±ΠΎΠ². ΠΠ°Π½ΠΎΡΡΠ΅ΡΠΎΠ» 14-Π°Π»ΡΡΠ° Π΄Π΅ΠΌΠ΅ΡΠΈΠ»Π°Π·Π° (CYP51) ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠΈΡΠΎΠΊΠΎ ΠΈΠ·Π²Π΅ΡΡΠ½ΠΎΠΉ ΠΌΠΈΡΠ΅Π½ΡΡ Π΄Π»Ρ ΠΏΡΠΎΡΠΈΠ²ΠΎΠ³ΡΠΈΠ±ΠΊΠΎΠ²ΡΡ
ΡΡΠ΅Π΄ΡΡΠ². ΠΠΏΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ SPR-Π±ΠΈΠΎΡΠ΅Π½ΡΠΎΡΡ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΡΡ ΡΠΎΠ±ΠΎΠΉ ΡΠ½ΠΈΠ²Π΅ΡΡΠ°Π»ΡΠ½ΡΠΉ ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½Ρ Π΄Π»Ρ ΡΠΊΡΠΈΠ½ΠΈΠ½Π³ΠΎΠ²ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ, ΡΠ΅Π»ΡΡ ΠΊΠΎΡΠΎΡΡΡ
ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΏΠΎΠΈΡΠΊ ΠΏΡΠΎΡΠΎΡΠΈΠΏΠΎΠ² Π½ΠΎΠ²ΡΡ
Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΡΡ
ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ. Π Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΠΌΠ΅ΡΠΎΠ΄ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π°ΡΠΏΠ΅ΠΊΡΡ Π²ΡΡΠΎΠΊΠΎΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠΊΡΠΈΠ½ΠΈΠ½Π³Π° Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠΈ Π½ΠΈΠ·ΠΊΠΎΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΡΡ
ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ ΠΏΡΠΈΡΠΎΠ΄Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΠΈΡΡ
ΠΎΠΆΠ΄Π΅Π½ΠΈΡ, Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½Π½ΠΎΠ³ΠΎ Π½Π° ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΈΠ΅ ΠΈΡ
Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ Ρ CYP51 C. krusei Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ SPR-Π±ΠΈΠΎΡΠ΅Π½ΡΠΎΡΠ°. ΠΠ°ΠΊ ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°ΡΡ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ, ΠΏΡΠΈ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠΈ Π²ΡΡΠΎΠΊΠΎΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠΊΡΠΈΠ½ΠΈΠ½Π³Π° ΠΎΡΠΎΠ±ΠΎΠ΅ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ ΡΠ»Π΅Π΄ΡΠ΅Ρ ΠΎΠ±ΡΠ°ΡΠ°ΡΡ Π½Π° ΡΡΠ΅ΠΏΠ΅Π½Ρ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΠΈ Π½Π°ΠΊΠ»ΠΎΠ½Π° ΡΠ΅Π½ΡΠΎΠ³ΡΠ°ΠΌΠΌΡ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ Π² ΡΠ°Π·Π΅ Π°ΡΡΠΎΡΠΈΠ°ΡΠΈΠΈ. ΠΠΏΠΈΡΠ°Π½Π½ΡΠ΅ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Ρ ΠΊ Π°Π½Π°Π»ΠΈΠ·Ρ Π΄Π°Π½Π½ΡΡ
Π²ΡΡΠΎΠΊΠΎΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠΊΡΠΈΠ½ΠΈΠ½Π³Π° ΠΌΠΎΠ³ΡΡ Π±ΡΡΡ ΠΏΠΎΠ»Π΅Π·Π½Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠΌ, ΡΠ°Π±ΠΎΡΠ°ΡΡΠΈΠΌ Ρ SPR-Π±ΠΈΠΎΡΠ΅Π½ΡΠΎΡΠ°ΠΌΠΈ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ
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