823 research outputs found

    The Research of Automation of the Process of Indexing Tax Returns

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    The article is devoted to the study of the automated search for information on tax declarations of different countries in public sources of various structures and the collection of information received in a single information storage. The first part of the paper describes methods of automated data collection and tasks that can be solved by these methods. The second part of the work describes the development of an algorithm for finding data on tax declarations from various sources and creating a prototype system that implements the data of the algorithm and provides access to the collected data.Β Keywords: search systems, indexation of tax declarations, information retrieval system

    Import Substitution Production of Semiconductor Silicon in Russia as a Tool to Reduce the risk of Money Laundering

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    The work is devoted to studying the need of creation a domestic production of polycrystalline, monocrystalline silicon and silicon wafers for the purposes of electronics and solar energy in the Russian Federation, as a part of the solution of a number of strategic objectives. In addition, the work discusses the question of import substitution as a means of combating money-laundering.Β Keywords: semiconductor silicon, polycrystalline silicon, monocrystalline silicon, import substitution, money launderin

    Development of an Automated Approach for Updating of the Annual Runoff Module Map

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    Several Russian Hydropower Design and Research Institutes have recently fulfilled studies of hydropower potential estimation for NorthWest, Caucasian and Angara River’s regions in Russia. An approach to automate the calculation of river flow characteristics, based on the usage of annual flow rate map, was proposed and tested by the authors for the aims of the studies.Annual river flow characteristics together with the terrain data are the most important data sources for evaluation of the hydropower potential.A set of requirements was made for the approach and for automation of annual flow rate maps creation in order to provide ability for updates in every 5-10 years.A problem of lack of hydrological data for small and medium sized rivers was faced. To determine the hydrological characteristics the Russian code specification "Determination of Design Hydrological Performance" was used for the conditions of the lack of hydrological data, methods of spatial interpolation were also used.To solve the problems it is necessary to define the parameters of the annual flow distribution: average annual flow, variation coefficient, coefficient of skewness.Mapping is based on the assumption of a smooth change of annual flow rate for any territory in accordance with the distribution of climatic and physiographic factors (topography, soil, groundwater depth, etc.).Milestones of flow rate mapping included: preparation of hydrological initial data; creating of the updated flow rate maps; determination of the corrections to the influence of local azonal factors; estimation of the accuracy of flow characteristics calculations.In order to update the annual flow rate maps a special GIS application β€œHydrologist” was created. The GIS application includes computer-assisted tool for processing the hydrological data, import/export tools, tools for analysis of area zoning data, tools for analysis of annual flow rate values in centroids of drainage-basins, location of water stage gauges, also the old and updated flow rate maps.The article deals with the approach description, main problems that were faced and presenting the results.The technology has been applied for North-West, Volga and Siberian Federal Districts in Russia. Comparison of the created annual flow rate map with the previously used map shows that the updated map is better of acquiring hydrological data for small and medium sized rivers

    Mid-range adiabatic wireless energy transfer via a mediator coil

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    A technique for efficient mid-range wireless energy transfer between two coils via a mediator coil is proposed. By varying the coil frequencies three resonances are created: emitter-mediator (EM), mediator-receiver (MR) and emitter-receiver (ER). If the frequency sweeps are adiabatic and such that the ER resonance precedes the MR resonance, the energy flows sequentially along the chain emitter-mediator-receiver. If the MR resonance precedes the ER resonance, then the energy flows directly from the emitter to the receiver via the ER resonance; then the losses from the mediator are suppressed. This technique is robust to noise, resonant constraints and external interferences

    Identification of dynamic errors-in-variables bilinear systems of fractional order

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    An approach for the identification of dynamic single-input single-output bilinear discrete-time fractional order system models within the errors-in-variables framework for the case of white input and output noise sequences is presented. A criterion is obtained that allows obtaining highly consistent estimates of the parameters of the system.The authors gratefully acknowledge the contributions of prof. O.A. Katsyuba in improving the article

    Identification of dynamic errors-in-variables bilinear systems of fractional order

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    An approach for the identification of dynamic single-input single-output bilinear discrete-time fractional order system models within the errors-in-variables framework for the case of white input and output noise sequences is presented. A criterion is obtained that allows obtaining highly consistent estimates of the parameters of the system.The authors gratefully acknowledge the contributions of prof. O.A. Katsyuba in improving the article

    Primary Sequences of Protein-Like Copolymers: Levy Flight Type Long Range Correlations

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    We consider the statistical properties of primary sequences of two-letter HP copolymers (H for hydrophobic and P for polar) designed to have water soluble globular conformations with H monomers shielded from water inside the shell of P monomers. We show, both by computer simulations and by exact analytical calculation, that for large globules and flexible polymers such sequences exhibit long-range correlations which can be described by Levy-flight statistics.Comment: 4 pages, including 2 figures; several references added, some formulations improve

    Orbit equivalence rigidity for ergodic actions of the mapping class group

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    We establish orbit equivalence rigidity for any ergodic, essentially free and measure-preserving action on a standard Borel space with a finite positive measure of the mapping class group for a compact orientable surface with higher complexity. We prove similar rigidity results for a finite direct product of mapping class groups as well.Comment: 11 pages, title changed, a part of contents remove

    Exact Lagrangian submanifolds in simply-connected cotangent bundles

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    We consider exact Lagrangian submanifolds in cotangent bundles. Under certain additional restrictions (triviality of the fundamental group of the cotangent bundle, and of the Maslov class and second Stiefel-Whitney class of the Lagrangian submanifold) we prove such submanifolds are Floer-cohomologically indistinguishable from the zero-section. This implies strong restrictions on their topology. An essentially equivalent result was recently proved independently by Nadler, using a different approach.Comment: 28 pages, 3 figures. Version 2 -- derivation and discussion of the spectral sequence considerably expanded. Other minor change

    Π’Ρ‹ΡΠΎΠΊΠΎΠΏΡ€ΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΉ скрининг с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ оптичСского SPR-биосСнсора низкомолСкулярных соСдинСний Π½Π° взаимодСйствиС с CYP51 Candida krusei

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    The opportunistic fungus Candida krusei is the causative agent of nosocomial infections characterized by high mortality and development of resistance to drugs of the azole class. Therefore, develjoment of non-azole antifungal agents against resistant fungal strains is extremly important. Lanosterol 14-alpha demethylase (CYP51) is a well-known antifungal target. The optical SPR biosensor is a universal tool for screening studies in search of new drug prototypes. This paper presents the methodological aspects of high-hroughput SPR based screening of a library of low molecular weight compounds of natural origin for their interaction with C. krusei CYP51. It has been shown that when performing high-throughput screening, a researcher should pay special attention to the degree of a sensorgram curvature in the association phase. The described approaches to the analysis of high throughput screening data can be useful for researchers working with SPR biosensors from various manufacturers.Условно-ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π½Ρ‹ΠΉ Π³Ρ€ΠΈΠ± Candida krusei (C. krusei) являСтся Π²ΠΎΠ·Π±ΡƒΠ΄ΠΈΡ‚Π΅Π»Π΅ΠΌ Π½ΠΎΠ·ΠΎΠΊΠΎΠΌΠΈΠ°Π»ΡŒΠ½Ρ‹Ρ… ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΉ, Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ΠΈΠ·ΡƒΡŽΡ‰ΠΈΡ…ΡΡ высокой Π»Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒΡŽ. Π’ послСднСС врСмя Π½Π°Π±Π»ΡŽΠ΄Π°Π΅Ρ‚ΡΡ тСндСнция ΠΊ ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΡŽ Π΄ΠΎΠ»ΠΈ ΡˆΡ‚Π°ΠΌΠΌΠΎΠ² Π΄Ρ€ΠΎΠΆΠΆΠ΅Π²Ρ‹Ρ… Π³Ρ€ΠΈΠ±ΠΎΠ², рСзистСнтных ΠΊ ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚Π°ΠΌ класса Π°Π·ΠΎΠ»ΠΎΠ². ΠŸΠΎΡΡ‚ΠΎΠΌΡƒ поиск ΠΏΠΎΡ‚Π΅Π½Ρ†ΠΈΠ°Π»ΡŒΠ½Ρ‹Ρ… ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠ³Ρ€ΠΈΠ±ΠΊΠΎΠ²Ρ‹Ρ… соСдинСний нСазольной ΠΏΡ€ΠΈΡ€ΠΎΠ΄Ρ‹ являСтся Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹ΠΌ Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½ΠΈΠ΅ΠΌ исслСдований ΠΏΡ€ΠΈ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ Π½ΠΎΠ²Ρ‹Ρ… эффСктивных тСрапСвтичСских срСдств Π² ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΠΈ рСзистСнтных ΡˆΡ‚Π°ΠΌΠΌΠΎΠ² Π³Ρ€ΠΈΠ±ΠΎΠ². ЛаностСрол 14-Π°Π»ΡŒΡ„Π° Π΄Π΅ΠΌΠ΅Ρ‚ΠΈΠ»Π°Π·Π° (CYP51) являСтся ΡˆΠΈΡ€ΠΎΠΊΠΎ извСстной мишСнью для ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠ³Ρ€ΠΈΠ±ΠΊΠΎΠ²Ρ‹Ρ… срСдств. ΠžΠΏΡ‚ΠΈΡ‡Π΅ΡΠΊΠΈΠ΅ SPR-биосСнсоры ΠΏΡ€Π΅Π΄ΡΡ‚Π°Π²Π»ΡΡŽΡ‚ собой ΡƒΠ½ΠΈΠ²Π΅Ρ€ΡΠ°Π»ΡŒΠ½Ρ‹ΠΉ инструмСнт для скрининговых исслСдований, Ρ†Π΅Π»ΡŒΡŽ ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… являСтся поиск ΠΏΡ€ΠΎΡ‚ΠΎΡ‚ΠΈΠΏΠΎΠ² Π½ΠΎΠ²Ρ‹Ρ… лСкарствСнных соСдинСний. Π’ Π΄Π°Π½Π½ΠΎΠΉ Ρ€Π°Π±ΠΎΡ‚Π΅ прСдставлСны мСтодичСскиС аспСкты Π²Ρ‹ΡΠΎΠΊΠΎΠΏΡ€ΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ скрининга Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ низкомолСкулярных соСдинСний ΠΏΡ€ΠΈΡ€ΠΎΠ΄Π½ΠΎΠ³ΠΎ происхоТдСния, Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½Π½ΠΎΠ³ΠΎ Π½Π° установлСниС ΠΈΡ… взаимодСйствия с CYP51 C. krusei с использованиСм SPR-биосСнсора. Как ΠΏΠΎΠΊΠ°Π·Ρ‹Π²Π°ΡŽΡ‚ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹, ΠΏΡ€ΠΈ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠΈ Π²Ρ‹ΡΠΎΠΊΠΎΠΏΡ€ΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ скрининга особоС Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ слСдуСт ΠΎΠ±Ρ€Π°Ρ‰Π°Ρ‚ΡŒ Π½Π° ΡΡ‚Π΅ΠΏΠ΅Π½ΡŒ выраТСнности Π½Π°ΠΊΠ»ΠΎΠ½Π° сСнсограммы взаимодСйствия Π² Ρ„Π°Π·Π΅ ассоциации. ΠžΠΏΠΈΡΠ°Π½Π½Ρ‹Π΅ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Ρ‹ ΠΊ Π°Π½Π°Π»ΠΈΠ·Ρƒ Π΄Π°Π½Π½Ρ‹Ρ… Π²Ρ‹ΡΠΎΠΊΠΎΠΏΡ€ΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ скрининга ΠΌΠΎΠ³ΡƒΡ‚ Π±Ρ‹Ρ‚ΡŒ ΠΏΠΎΠ»Π΅Π·Π½Ρ‹ исслСдоватСлям, Ρ€Π°Π±ΠΎΡ‚Π°ΡŽΡ‰ΠΈΠΌ с SPR-биосСнсорами Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Ρ… ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ
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